Not known Details About https://www.ceesdekker.net
Not known Details About https://www.ceesdekker.net
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‘Indeed, that may be about proper. I try to find a Bodily knowledge of biological devices in a base-up way. I think you may distinguish three traces of investigate in my group at the moment. The 1st concerns chromosome construction: How does one obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic mobile? We've got formulated visualisation techniques that enable us to review how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can build up chromosomes.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Round the identical time, the team of Paul McEuen, who was then based mostly in the College of California, Berkeley, showed similar effects on ropes of bundled nanotubes. Dependant upon the wrapping angle, nanotubes can are available metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed applying scanning tunnelling spectroscopy experiments.
Considering the fact that 2000, Dekker has shifted the primary concentration of his work in direction of biophysics wherever he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, together with via the lengthy-phrase point of view a large number of attention-grabbing discoveries may be anticipated On this discipline.[five] Latest strains of investigate in his biophysics team are in the areas of:[6]
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Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry
You are a Christian. If you could potentially make this type of synthetic mobile, would you be one particular stage nearer to God, or would the function of God have diminished to some degree once again?
Nanopores symbolize an elegant and flexible Instrument to measure single molecules. We research novel detection modes with solid-state nanopores along with several ways to measure proteins with nanopores. Projects encompass the following:
Let's say, rather than applying typical top-down silicon electronics, transistors may very well be constructed from The underside up utilizing one organic molecules as being the switching components? This concept, which turned The idea of now’s area of molecular electronics, to start with emerged inside the nineteen seventies.
There was a single dilemma however — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule degree, conducting polymers have been in fact not these good conductors, which was alternatively disappointing. We So broadened our view to test to uncover extra promising molecules.
An built-in microfluidic System for quantifying drug permeation across biomimetic vesicle membranes
1999, very first measurement of your wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for just a new Luttinger description of interacting electrons in nanotubes
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of extended-array conformational modifications in Mre11/DNA restore complexes; and to start with power measurements over a DNA https://www.ceesdekker.net molecule in a nanopore
‘I am driven by question and queries. On a fabric stage I come across responses in physics, but I experience my deepest pleasure with God. That religion also drives my science And just how I manage people today.